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HDAC5 Polyclonal Antibody

CAT: 0749-ABP51503-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51503-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 5 encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. HDAC5 is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for HDAC5.
Description
Rabbit Anti-HDAC5 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
HDAC5; KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9
Gene ID
10014
Accession Number
Q9UQL6
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human HDAC5 around the non-phosphorylation site of S498
Clonality
Polyclonal
Tag
Histone deacetylase 5
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
122kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
HDAC5 Polyclonal Antibody detects endogenous levels of HDAC5 protein.
Observed Molecular Weight
122
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
HDAC5; KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9UQL6
Isotype
Rabbit IgG

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