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HDAC4 Polyclonal Antibody

CAT: 0749-ABP51502-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51502-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 4 encoded by HDAC4 belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. Histone deacetylase 4 does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Description
Rabbit Anti-HDAC4 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
HDAC4; KIAA0288; Histone deacetylase 4; HD4
Gene ID
9759
Accession Number
P56524
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human HDAC4 around the non-phosphorylation site of S632
Clonality
Polyclonal
Tag
Histone deacetylase 4
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
119kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
HDAC4 Polyclonal Antibody detects endogenous levels of HDAC4 protein.
Observed Molecular Weight
119
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
HDAC4; KIAA0288; Histone deacetylase 4; HD4
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P56524
Isotype
Rabbit IgG

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