Products for Research Use Only

COL11A2 Polyclonal Antibody

CAT: 0749-ABP51020-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51020-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
COL11A2 encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53) . Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
Description
Rabbit Anti-COL11A2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
COL11A2; Collagen alpha-2 (XI) chain
Gene ID
1302
Accession Number
P13942
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of human COL11A2 at AA range: 1180-1260
Clonality
Polyclonal
Tag
Collagen alpha-2 (XI) chain
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
171kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
COL11A2 Polyclonal Antibody detects endogenous levels of COL11A2 protein.
Observed Molecular Weight
171
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
COL11A2; Collagen alpha-2 (XI) chain
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P13942
Isotype
Rabbit IgG

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