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COL11A2 Polyclonal Antibody

CAT: 0965-JOT-AP02059-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02059-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
COL11A2 encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
CAS Number
9007-83-4
Synonyms
COL11A2; Collagen alpha-2(XI) chain
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Collagen XI alpha2. AA range:1211-1260
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
171775
Antibody Type
Primary antibody
Isotype
IgG

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