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CLC-4 Polyclonal Antibody

CAT: 0749-ABP50992-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP50992-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. CLCN4 is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.
Description
Rabbit Anti-CLC-4 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CLCN4; H (+) /Cl (-) exchange transporter 4; Chloride channel protein 4; ClC-4; Chloride transporter ClC-4
Gene ID
1183
Accession Number
P51793
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human CLC-4 at AA range: 190-270
Clonality
Polyclonal
Tag
H (+)
Applications
WB, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
85kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CLC-4 Polyclonal Antibody detects endogenous levels of CLC-4 protein.
Observed Molecular Weight
85
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
CLCN4; H (+) /Cl (-) exchange transporter 4; Chloride channel protein 4; ClC-4; Chloride transporter ClC-4
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P51793
Isotype
Rabbit IgG

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