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CLC-7 Polyclonal Antibody

CAT: 0749-ABP50994-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP50994-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The product of CLCN7 belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. CLCN7 encodes chloride channel 7. Defects in CLCN7 are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
Description
Rabbit Anti-CLC-7 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CLCN7; H (+) /Cl (-) exchange transporter 7; Chloride channel 7 alpha subunit; Chloride channel protein 7; ClC-7
Gene ID
1186
Accession Number
P51798
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the N-terminal region of human CLC-7 at AA range: 10-90
Clonality
Polyclonal
Tag
H (+)
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
90kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CLC-7 Polyclonal Antibody detects endogenous levels of CLC-7 protein.
Observed Molecular Weight
90
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
CLCN7; H (+) /Cl (-) exchange transporter 7; Chloride channel 7 alpha subunit; Chloride channel protein 7; ClC-7
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P51798
Isotype
Rabbit IgG

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