Products for Research Use Only
RegisterLogin

Cerebellin 2 Polyclonal Antibody

CAT: 0749-ABP50956-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP50956-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3), and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. CER and it metabolite des-Ser1-cerebellin are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other's degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for CER in the pathology of these diseases.
Description
Rabbit Anti-Cerebellin 2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CBLN2; Cerebellin-2
Gene ID
147381
Accession Number
Q8IUK8
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Synthesized peptide derived from the C-terminal region of human Cerebellin 2 at AA range: 130-210
Clonality
Polyclonal
Tag
Cerebellin-2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
24kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Cerebellin 2 Polyclonal Antibody detects endogenous levels of Cerebellin 2 protein.
Observed Molecular Weight
24
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
CBLN2; Cerebellin-2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q8IUK8
Isotype
Rabbit IgG

Related Products

CatalogName
ABP50957-01Cerebellin 4 Polyclonal Antibody
ABP50955-01Cerebellin 1 Polyclonal Antibody
ABP56169-01Cerebellin 3 Polyclonal Antibody
KTE62429-01ELISA kit for Human Cerebellin-1 (CBLN1)
ABP58712-01Gremlin-2 Polyclonal Antibody
ABP51705-01LATS1/2 Polyclonal Antibody
ABP51438-01GluR-2 Polyclonal Antibody
ABP53280-01FGF-2 Polyclonal Antibody
ABP50680-01APLP-2 Polyclonal Antibody
ABP55287-01Msx-2 Polyclonal Antibody

Alternative Products

CatalogName
GTR18198736Cerebellin 4 Polyclonal Antibody
JOT-AP01709-01Cerebellin 2 Polyclonal Antibody
JOT-AP01710-01Cerebellin 3 Polyclonal Antibody
MBS8521849-01Cerebellin 1 Polyclonal Antibody
AMM05744GPolyclonal Cerebellin 4 Antibody

Popular Products