Msx-2 Polyclonal Antibody

• Background:

  MSX2 encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in MSX2 are associated with parietal foramina 1 and craniosynostosis type 2.

• Description:

  Rabbit Anti-Msx-2 Polyclonal Antibody

• Product Name Alternative:

  MSX2; HOX8; Homeobox protein MSX-2; Homeobox protein Hox-8

• Gene ID:

  4488

• Accession Number:

  P35548

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from the Internal region of human Msx-2

• Clonality:

  Polyclonal

• Tag:

  Homeobox protein MSX-2

• Applications:

  WB, IHC, IF, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  28kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  Msx-2 Polyclonal Antibody detects endogenous levels of Msx-2 protein.

• Observed Molecular Weight:

  28

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200

• Other Product Names:

  MSX2; HOX8; Homeobox protein MSX-2; Homeobox protein Hox-8

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/P35548

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG