Products for Research Use Only

Bcl-w Polyclonal Antibody

CAT: 0749-ABP50761-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP50761-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BCL2L2 encodes a member (BCL2 like 2) of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of BCL2L2 in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly (A) binding protein, nuclear 1) gene.
Description
Rabbit Anti-Bcl-w Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
BCL2L2; BCLW; KIAA0271; Bcl-2-like protein 2; Bcl2-L-2; Apoptosis regulator Bcl-W
Gene ID
599
Accession Number
Q92843
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the C-terminal region of human Bcl-w at AA range: 100-180
Clonality
Polyclonal
Tag
Bcl-2-like protein 2
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
25kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Bcl-w Polyclonal Antibody detects endogenous levels of Bcl-w protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
BCL2L2; BCLW; KIAA0271; Bcl-2-like protein 2; Bcl2-L-2; Apoptosis regulator Bcl-W
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q92843
Isotype
Rabbit IgG

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