Bcl-2 Polyclonal Antibody

• Background:

  BCL2 encodes an integral outer mitochondrial membrane protein (BCL2, apoptosis regulator) that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

• Description:

  Rabbit Anti-Bcl-2 Polyclonal Antibody

• Product Name Alternative:

  BCL2; Apoptosis regulator Bcl-2

• Gene ID:

  596

• Accession Number:

  P10415

• Reactivity:

  Human, Mouse, Rat, Chicken

• Immunogen:

  Synthesized peptide derived from human Bcl-2 around the non-phosphorylation site of T69

• Clonality:

  Polyclonal

• Tag:

  Apoptosis regulator Bcl-2

• Applications:

  WB, IHC, IF, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  26kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  Bcl-2 Polyclonal Antibody detects endogenous levels of Bcl-2 protein.

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.

• Other Product Names:

  BCL2; Apoptosis regulator Bcl-2

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/P10415

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG