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APC5 Polyclonal Antibody

CAT: 0749-ABP50677-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP50677-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ANAPC5 encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein (anaphase promoting complex subunit 5) is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
Description
Rabbit Anti-APC5 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
ANAPC5; APC5; Anaphase-promoting complex subunit 5; APC5; Cyclosome subunit 5
Gene ID
51433
Accession Number
Q9UJX4
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human APC5 at AA range: 120-200
Clonality
Polyclonal
Tag
Anaphase-promoting complex subunit 5
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
85kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
APC5 Polyclonal Antibody detects endogenous levels of APC5 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
Other Product Names
ANAPC5; APC5; Anaphase-promoting complex subunit 5; APC5; Cyclosome subunit 5
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9UJX4
Isotype
Rabbit IgG

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