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APC4 Polyclonal Antibody

CAT: 0749-ABP57788-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57788-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene. APC4 (Anaphase Promoting Complex Subunit 4) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Cell Cycle, Mitotic.
Description
Rabbit Anti-APC4 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Anaphase-promoting complex subunit 4 (APC4) ; Cyclosome subunit 4
Gene ID
29945
Accession Number
Q9UJX5
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human APC4 protein
Clonality
Polyclonal
Tag
APC4
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
88kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of APC4 protein
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Anaphase-promoting complex subunit 4 (APC4) ; Cyclosome subunit 4
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9UJX5
Isotype
Rabbit IgG

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