Crocin

CAT: 0804-HY-N0697-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0697-01Size:5 mg
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Description
Crocin (Crocin I) is an orally active natural product that can be isolated from the stigma of Crocus sativus. Crocin inhibits tumor cell proliferation and promotes apoptosis through JAK pathway. Crocin has anti-inflammatory, antioxidant and antitumor activities [1][2].
CAS Number
[42553-65-1]
Product Name Alternative
Crocin I
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Endogenous Metabolite; JAK
Type
Natural Products
Related Pathways
Apoptosis; Epigenetics; JAK/STAT Signaling; Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/crocin.html
Purity
99.68
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O[C@@H]([C@H](O)[C@H]1O)[C@H](O[C@H]1OC(/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C(O[C@@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)=O)=O)CO[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO
Molecular Formula
C44H64O24
Molecular Weight
976.96
Precautions
H302, H315, H319, H335
References & Citations
[1]Zaghloul MS, et al. Crocin attenuates lung inflammation and pulmonary vascular dysfunction in a rat model of bleomycin-induced pulmonary fibrosis. Life Sci. 2019 Aug 26:116794.|[2]Yang H, et al. Crocin exerts anti-tumor effect in colon cancer cells via repressing the JAK pathway. Eur J Histochem. 2023 Sep 12;67 (3) :3697.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
Launched

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