Products for Research Use Only
RegisterLogin

Crocetin (Standard)

CAT: 0804-HY-N2072R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N2072R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Crocetin (Standard) (TransCrocetin (Standard) ) is an aglycone of crocin. Crocetin (Standard) is orally active and brain-penetrant. Crocetin (Standard) shows strong NMDA receptor affinity and channel opening activity. Crocetin (Standard) can downregulate the proinflammatory cytokines and COX-2 exoression. Crocetin (Standard) can inhibit apoptosis and activation of MAPK. Crocetin (Standard) can delay delays brain and body aging. Crocetin (Standard) can be used for the researches of cancer, neurological disease and inflammation, such as cervical cancer and ischemia[1][2][3][4].
CAS Number
27876-94-4
Product Name Alternative
Transcrocetin (Standard) ; trans-Crocetin (Standard)
UNSPSC
12352211
Target
Apoptosis; COX; iGluR; p38 MAPK; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/crocetin-standard.html
Purity
96.79
Smiles
O=C(O)/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C(O)=O
Molecular Formula
C20H24O4
Molecular Weight
328.40
References & Citations
[1]Chen B, et al. Crocetin downregulates the proinflammatory cytokines in methylcholanthrene-induced rodent tumor model and inhibits COX-2 expression in cervical cancer cells. Biomed Res Int. 2015;2015:829513.|[2]Crocetin, a carotenoid derivative, inhibits retinal ischemic damage in mice. Eur J Pharmacol. 2013 Mar 5;703 (1-3) :1-10.|[3]Choudhary S, et al. Crocetin Delays Brain and Body Aging by Increasing Cellular Energy Levels in Aged C57BL/6J Mice. ACS Pharmacol Transl Sci. 2024 Sep 11;7 (10) :3017-3033.|[4]Lautenschläger M, et al. Intestinal formation of trans-crocetin from saffron extract (Crocus sativus L.) and in vitro permeation through intestinal and blood brain barrier. Phytomedicine. 2015 Jan 15;22 (1) :36-44.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Isoform
COX-2; NMDA Receptor

Related Products

CatalogName
HY-N6904RCrocetin monomethyl ester (Standard)
HY-N2072-01Crocetin
HY-N10991-01Crocetin dialdehyde
HY-42937-01Crocetin (meglumine)
HY-16502-01Crocetin (disodium)
HY-N9372-01Crocetin β-D-glucopyranoside
HY-N6904-01Crocetin monomethyl ester
HY-N0697R-01Crocin (Standard)
HY-N9371RCrocin IV (Standard)
HY-N6644RCrocin III (Standard)

Alternative Products

CatalogName
BA8418-5Crocetin
T82669-01Crocetin dialdehyde
T75267-01Crocetin meglumine
371316Crocetin discontinued
M38769Crocetin methylester

Popular Products