OCLN rabbit pAb

• Background :

  This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]

• Description :

  This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1. 5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],

• UniProt :

  Q16625

• Swiss Prot :

  Q16625

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from part region of human protein. AA350-400

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.

• Molecular Weight :

  57kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  57kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Multi-pass membrane protein . Cell junction, tight junction .

• Gene ID (Human) :

  100506658