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RTN2 rabbit pAb

CAT: 0855-ES11411-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11411-01Size:50 µL
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Background
This gene belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Apr 2012]
Description
This gene belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Apr 2012],
UniProt
O75298
Swiss Prot
O75298
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 391-440
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
59kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
59kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma ; Multi-pass membrane protein . Cell membrane, sarcolemma, T-tubule ; Multi-pass membrane protein . Cytoplasm, myofibril, sarcomere, Z line . Cytoplasm, cytoskeleton . Localizes to intermediate filaments in mononucleated myoblasts and to Z lines in mature myotubes. .
Gene ID (Human)
6253

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