RTN2 rabbit pAb

• Background :

  This gene belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Apr 2012]

• Description :

  This gene belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Apr 2012],

• UniProt :

  O75298

• Swiss Prot :

  O75298

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from human protein . at AA range: 391-440

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  59kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  59kD

• Fragment :

  IgG

• Subcellular Location :

  Endoplasmic reticulum membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma ; Multi-pass membrane protein . Cell membrane, sarcolemma, T-tubule ; Multi-pass membrane protein . Cytoplasm, myofibril, sarcomere, Z line . Cytoplasm, cytoskeleton . Localizes to intermediate filaments in mononucleated myoblasts and to Z lines in mature myotubes. .

• Gene ID (Human) :

  6253