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FKBP2 rabbit pAb

CAT: 0855-ES11313-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11313-01Size:50 µL
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Background
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
Description
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008],
UniProt
P26885
Swiss Prot
P26885
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 80-160
Target
FKBP2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
15kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
15kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Peripheral membrane protein .
Gene ID (Human)
2286

UniProtKB · P26885

Peptidyl-prolyl cis-trans isomerase FKBP2

FKBP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P26885
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FKBP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PPIase FKBP2
EC number
5.2.1.8
Processing
Precursor
Secondary accessions
Q5BJH9, Q9BTS7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Endoplasmic reticulumMembrane

Molecular function

IsomeraseRotamase

Domain

Signal

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