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R4RL2 rabbit pAb

CAT: 0855-ES11214-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11214-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:May play a role in regulating axonal regeneration and plasticity in the adult central nervous system., PTM:Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein., similarity:Belongs to the Nogo receptor family., similarity:Contains 8 LRR (leucine-rich) repeats., subcellular location:Localized to the surface of neurons, including axons., tissue specificity:Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.
Description
Function: May play a role in regulating axonal regeneration and plasticity in the adult central nervous system. PTM: Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein. similarity: Belongs to the Nogo receptor family. similarity: Contains 8 LRR (leucine-rich) repeats. subcellular location: Localized to the surface of neurons, including axons. tissue specificity: Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.
UniProt
Q86UN3
Swiss Prot
Q86UN3
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 290-370
Target
R4RL2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
46kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
46kD
Fragment
IgG
Subcellular Location
Cell membrane ; Lipid-anchor, GPI-anchor . Membrane raft . Cell projection, dendrite . Perikaryon . Cell projection, axon . Localized to the surface of neurons, including axons. Detected close to synapses, but is excluded from synapses. .
Gene ID (Human)
349667