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TLN2 rabbit pAb

CAT: 0855-ES11125-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11125-01Size:50 µL
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Background
This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008]
Description
This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008],
UniProt
Q9Y4G6
Swiss Prot
Q9Y4G6
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF
Concentration
1 mg/ml
Dilution
IHC-p 1:50-300
Molecular Weight
279kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
279kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cell junction, focal adhesion . Cell junction, synapse . Cell membrane; Peripheral membrane protein; Cytoplasmic side . Cytoplasm, cytoskeleton . Focal adhesion plaques and synapses (PubMed:12422219) . .
Gene ID (Human)
83660

UniProtKB · Q9Y4G6

Talin-2

TLN2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y4G6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TLN2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NLB8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell junctionCell membraneCytoplasmCytoskeletonMembraneSynapse

PTM

Phosphoprotein

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MBS9517428-01TLN2 Rabbit Polyclonal Antibody
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