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FKB1B rabbit pAb

CAT: 0855-ES11010-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11010-01Size:50 µL
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Background
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008],
UniProt
P68106
Swiss Prot
P68106
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein AA range: 1-50
Target
FKB1B
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
11kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
11kD
Fragment
IgG
Subcellular Location
Cytoplasm . Sarcoplasmic reticulum .
Gene ID (Human)
2281

UniProtKB · P68106

Peptidyl-prolyl cis-trans isomerase FKBP1B

FKB1B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P68106
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FKBP1B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PPIase FKBP1B
EC number
5.2.1.8
Processing
—
Secondary accessions
Q13664, Q16645, Q53TM2, Q9BQ40
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmSarcoplasmic reticulum

Molecular function

IsomeraseRotamase

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