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PGCB rabbit pAb

CAT: 0855-ES10936-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10936-01Size:50 µL
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Background
This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Description
This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011],
UniProt
Q96GW7
Swiss Prot
Q96GW7
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
100kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
100kD
Fragment
IgG
Subcellular Location
[Isoform 1]: Secreted, extracellular space, extracellular matrix.; [Isoform 2]: Membrane; Lipid-anchor, GPI-anchor.
Gene ID (Human)
63827

UniProtKB · Q96GW7

Brevican core protein

PGCB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96GW7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BCAN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
D3DVC2, Q5SZ10, Q5T3I5, Q8TBB9, Q9HBK1, Q9HBK4
Protein keywords

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoproteinGPI-anchorLipoproteinPhosphoproteinProteoglycan

Domain

EGF-like domainImmunoglobulin domainRepeatSignalSushi

Cellular component

Extracellular matrixMembraneSecreted

Ligand

Hyaluronic acidLectin

Technical term

Proteomics identificationReference proteome

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