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HES4 rabbit pAb

CAT: 0855-ES10933-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10933-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Domain:Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG) ., domain:The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins., function:Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'., similarity:Contains 1 basic helix-loop-helix (bHLH) domain., similarity:Contains 1 Orange domain., subunit:Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.
Description
Domain: Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG). Domain: The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins. function: Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. similarity: Contains 1 basic helix-loop-helix (bHLH) domain. similarity: Contains 1 Orange domain. subunit: Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.
UniProt
Q9HCC6
Swiss Prot
Q9HCC6
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
HES4
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
24kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
24kD
Fragment
IgG
Subcellular Location
Nucleus .
Gene ID (Human)
57801

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