FAM3B rabbit pAb

CAT: 0855-ES10908-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0855-ES10908-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Function:Has delayed effects on beta-cell function, inhibiting basal insulin secretion from a beta-cell line in a dose-dependent manner., miscellaneous:2 N-termini have been observed in the mature protein: the first at Glu-30, resulting from signal peptide cleavage, the second at Ser-46., similarity:Belongs to the FAM3 family., subcellular location:Localized in discrete vesicular and perinuclear structure., tissue specificity:Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis.

Description

Function: Has delayed effects on beta-cell function, inhibiting basal insulin secretion from a beta-cell line in a dose-dependent manner. miscellaneous: 2 N-termini have been observed in the mature protein: the first at Glu-30, resulting from signal peptide cleavage, the second at Ser-46. similarity: Belongs to the FAM3 family. subcellular location: Localized in discrete vesicular and perinuclear structure. tissue specificity: Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis.

UniProt

P58499

Swiss Prot

P58499

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from part region of human protein AA range: 21-70

Target

FAM3B

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

25kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

25kD

Fragment

IgG

Subcellular Location

Secreted. Present in insulin secretory granules and likely cosecreted with insulin. Localized in discrete vesicular and perinuclear structure.

Gene ID (Human)

54097

UniProtKB · P58499

Protein FAM3B

FAM3B_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P58499
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: FAM3B
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: —

Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

Molecular function

Cytokine

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoprotein

Ligand

Lectin

Cellular component

Secreted

Domain

Signal

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Alternative Products

Catalog	Name
MBS8544222-01	FAM3B Rabbit pAb
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GTR18054347-01	FAM3B rabbit pAb Antibody
E28PN1962	FAM3B Rabbit Polyclonal Antibody
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