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HIPK2 rabbit pAb

CAT: 0855-ES10814-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10814-01Size:50 µL
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Background
Homeodomain interacting protein kinase 2 (HIPK2) Homo sapiens This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Description
Homeodomain interacting protein kinase 2 (HIPK2) Homo sapiens This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
UniProt
Q9H2X6
Swiss Prot
Q9H2X6
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
131kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
131kD
Fragment
IgG
Subcellular Location
Nucleus, PML body . Cytoplasm. Concentrated in PML/POD/ND10 nuclear bodies. Small amounts are cytoplasmic.
Gene ID (Human)
28996

UniProtKB · Q9H2X6

Homeodomain-interacting protein kinase 2

HIPK2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9H2X6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HIPK2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
hHIPk2
EC number
2.7.11.1
Processing
—
Secondary accessions
Q75MR7, Q8WWI4, Q9H2Y1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisDNA damageHost-virus interactionTranscriptionTranscription regulation

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmNucleus

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

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