ASPM rabbit pAb
CAT:
855-ES10611-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ASPM rabbit pAb
- Description: This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],
- Gene ID: 259266
- UniProt: Q8IZT6
- Cellular Locus: Cytoplasm. Cytoplasm, cytoskeleton, spindle. Nucleus. The nuclear-cytoplasmic distribution could be regulated by the availability of calmodulin (By similarity). Localizes to spindle poles during mitosis (PubMed:19690332). Associates with microtubule minus ends (By similarity)..
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse,
- Immunogen: Synthesized peptide derived from human protein . at AA range: 1230-1310
- Clonality: Polyclonal
- Validated Applications: IHC, IF
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: IHC-p 1:50-300
- Molecular Weight: 382kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.