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TNNC2 rabbit pAb

CAT: 0855-ES10398-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10398-01Size:50 µL
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Background
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]
Description
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008],
UniProt
P02585
Swiss Prot
P02585
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
TNNC2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
17kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
17kD
Fragment
IgG
Subcellular Location
Cytosol, troponin complex
Gene ID (Human)
7125

UniProtKB · P02585

Troponin C, skeletal muscle

TNNC2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02585
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TNNC2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6FH92
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Acetylation

Ligand

CalciumMetal-binding

Disease

Disease variant

Molecular function

Muscle protein

Domain

Repeat