TNNC1 rabbit pAb
CAT:
855-ES12618-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TNNC1 rabbit pAb
- Description: Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008],
- Gene ID: 7134
- UniProt: P63316
- Cellular Locus: Nucleoplasm,mitochondrion,cytosol,troponin complex,actin cytoskeleton,contractile fiber,
- Host: Rabbit
- Species Reactivity: Human, Mouse
- Immunogen: Synthesized peptide derived from human TNNC1 AA range: 57-107
- Clonality: Polyclonal
- Validated Applications: WB
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1：500-2000
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.