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S4A7 rabbit pAb

CAT: 0855-ES10274-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10274-01Size:50 µL
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Background
This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]
Description
This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1: 1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012],
UniProt
Q9Y6M7
Swiss Prot
Q9Y6M7
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
133kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
133kD
Fragment
IgG
Subcellular Location
Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane ; Multi-pass membrane protein . Cell projection, stereocilium . Also described at the apical cell membrane. Localizes to the stereocilia of cochlear outer hair cells and to the lateral membrane of cochlear inner hair cells (By similarity) . .
Gene ID (Human)
9497

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