RAC2 rabbit pAb

• Background:

  This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP) -metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]

• Description:

  This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013],

• UniProt:

  P15153

• Swiss Prot:

  P15153

• Reactivity:

  Human; Mouse; Bovine; Bovine

• Immunogen:

  Synthesized peptide derived from human protein . at AA range: 130-210

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  21kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  21kD

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm. Membrane-associated when activated.

• Gene ID (Human):

  5880