Rac1/CDC42 (Phospho Ser71) rabbit pAb
CAT:
855-ES20202-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Rac1/CDC42 (Phospho Ser71) rabbit pAb
- Synonyms: Ras-related C3 botulinum toxin substrate 1 (Cell migration-inducing gene 5 protein;Ras-like protein TC25;p21-Rac1)
- Gene ID: 5879
- UniProt: P63000/P15153/P60763/P60953
- Cellular Locus: Cell membrane ; Lipid-anchor ; Cytoplasmic side. Melanosome. Cytoplasm. Cell projection, lamellipodium. Cell projection, dendrite. Cell junction, synapse. Nucleus. Inner surface of plasma membrane possibly with attachment requiring prenylation of the C-terminal cysteine (PubMed:1903399). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts. Localizes to the lamellipodium in a SH3RF1-dependent manner (By similarity). In macrophages, cytoplasmic location increases upon CSF1 stimulation (By similarity). Activation by GTP-binding promotes nuclear localization (PubMed:12551911)..
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthesized peptide derived from human Rac1/CDC42 (Phospho Ser71)
- Clonality: Polyclonal
- Validated Applications: WB, ELISA, IHC
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.