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ZPI rabbit pAb

CAT: 0855-ES10069-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10069-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2010]
Description
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2010],
UniProt
Q9UK55
Swiss Prot
Q9UK55
Reactivity
Human; Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 160-240
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
48kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
48kD
Fragment
IgG
Subcellular Location
Secreted.
Gene ID (Human)
51156

UniProtKB · Q9UK55

Protein Z-dependent protease inhibitor

ZPI_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UK55
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SERPINA10
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PZ-dependent protease inhibitor, PZI
EC number
—
Processing
Precursor
Secondary accessions
A5Z2A5, Q6UWX9, Q86U20
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Blood coagulationHemostasis

PTM

GlycoproteinPhosphoprotein

Molecular function

Heparin-bindingProtease inhibitorSerine protease inhibitor

Cellular component

Secreted

Domain

Signal

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