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KCNE1 rabbit pAb

CAT: 0855-ES10025-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10025-01Size:50 µL
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Background
Potassium voltage-gated channel subfamily E regulatory subunit 1 (KCNE1) Homo sapiens The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Description
Potassium voltage-gated channel subfamily E regulatory subunit 1 (KCNE1) Homo sapiens The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],
UniProt
P15382
Swiss Prot
P15382
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
Target
KCNE1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
14kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
14kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type I membrane protein . Apical cell membrane . Membrane raft . Colocalizes with KCNB1 at the plasma membrane (By similarity) . Targets to the membrane raft when associated with KCNQ1 (PubMed:20533308) . .
Gene ID (Human)
3753

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