NETO1 rabbit pAb

• Background:

  This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in mice encodes a protein that plays a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

• Description:

  This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in mice encodes a protein that plays a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],

• Gene ID:

  81832

• UniProt:

  Q8TDF5

• Cellular Locus:

  [Isoform 2]: Cell membrane ; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane. Component of the postsynaptic density (PSD) of excitatory synapses..; [Isoform 3]: Cell membrane ; Single-pass type I membrane protein.; [Isoform 1]: Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human protein . at AA range: 20-100

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  58kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  58 kD

• Subcellular Location:

  [Isoform 2]: Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, postsynaptic density membrane . Component of the postsynaptic density (PSD) of excitatory synapses. .; [Isoform 3]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 1]: Secreted .

• Gene ID (Human):

  81832

• SwissProt (Human):

  Q8TDF5