MAP1B rabbit pAb

• Background:

  This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq, Jul 2008]

• Description:

  This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq, Jul 2008],

• Gene ID:

  4131

• UniProt:

  P46821

• Cellular Locus:

  Cytoplasm, cytoskeleton. Cytoplasm. Cell junction, synapse. Cell projection, dendritic spine. Colocalizes with DAPK1 in the microtubules and cortical actin fibers..; [MAP1 light chain LC1]: Cytoplasm.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from human protein . at AA range: 480-560

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  IHC, IF

• Validated Applications:

  IHC, IF

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  IHC-p 1:50-300

• Molecular Weight:

  271kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  271 kD

• Subcellular Location:

  Cytoplasm, cytoskeleton . Cytoplasm . Cell junction, synapse . Cell projection, dendritic spine . Colocalizes with DAPK1 in the microtubules and cortical actin fibers. .; [MAP1 light chain LC1]: Cytoplasm .

• Gene ID (Human):

  4131

• SwissProt (Human):

  P46821