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RPA43 rabbit pAb

CAT: 0855-ES9603-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9603-01Size:50 µL
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Background
Function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters., similarity:Belongs to the eukaryotic RPA43 RNA polymerase subunit family., subunit:Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits (By similarity) . Interacts with RRN3/TIF-IA., tissue specificity:Widely expressed. Expressed in all fetal and adult tissues tested, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues.
Description
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters. similarity: Belongs to the eukaryotic RPA43 RNA polymerase subunit family. subunit: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits (By similarity). Interacts with RRN3/TIF-IA. tissue specificity: Widely expressed. Expressed in all fetal and adult tissues tested, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues.
UniProt
Q3B726
Swiss Prot
Q3B726
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
RPA43
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
37kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
37kD
Fragment
IgG
Subcellular Location
Nucleus, nucleolus .
Gene ID (Human)
221830

UniProtKB · Q3B726

DNA-directed RNA polymerase I subunit RPA43

RPA43_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q3B726
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POLR1F
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A0PJ45, B7Z724
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

DNA-directed RNA polymeraseNucleus

PTM

Phosphoprotein

Biological process

Transcription

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