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RPA40 rabbit pAb

CAT: 0855-ES8055-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8055-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Description
The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Product Name Alternative
POLR1C; POLR1E; DNA-directed RNA polymerases I and III subunit RPAC1; DNA-directed RNA polymerase I subunit C; RNA polymerases I and III subunit AC1; AC40; DNA-directed RNA polymerases I and III 40 kDa polypeptide; RPA40; RPA39; RPC40
UniProt
O15160
Swiss Prot
O15160
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human POLR1C. AA range:101-150
Target
RPA40
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
39kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
39kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
POLR1C; POLR1E; DNA-directed RNA polymerases I and III subunit RPAC1; DNA-directed RNA polymerase I subunit C; RNA polymerases I and III subunit AC1; AC40; DNA-directed RNA polymerases I and III 40 kDa polypeptide; RPA40; RPA39; RPC40
Gene ID (Human)
9533

UniProtKB · O15160

DNA-directed RNA polymerases I and III subunit RPAC1

RPAC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15160
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POLR1C
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
DNA-directed RNA polymerase I subunit C, RNA polymerases I and III subunit AC1
EC number
—
Processing
—
Secondary accessions
O75395, Q5JTE3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmDNA-directed RNA polymeraseNucleus

Disease

Disease variantLeukodystrophy

Biological process

Transcription

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