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DLG3 rabbit pAb

CAT: 0855-ES9589-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9589-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
Description
This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009],
UniProt
Q92796
Swiss Prot
Q92796
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
89kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
89kD
Fragment
IgG
Subcellular Location
Extracellular space, cytoplasm, plasma membrane, bicellular tight junction, ionotropic glutamate receptor complex, postsynaptic density, basolateral plasma membrane, growth cone, AMPA glutamate receptor complex, neuronal cell body, d
Gene ID (Human)
1741