DOC11 rabbit pAb

• Background :

  Domain:The DHR-2 domain is necessary for the GEF activity., function:Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP., miscellaneous:'Zizim' means 'spike' in Hebrew., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the DOCK family., similarity:Contains 1 DHR-1 (CZH-1) domain., similarity:Contains 1 DHR-2 (CZH-2) domain., similarity:Contains 1 PH domain., subunit:Interacts with CDC42.

• Description :

  Domain: The DHR-2 domain is necessary for the GEF activity. function: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. miscellaneous: 'Zizim' means 'spike' in Hebrew. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the DOCK family. similarity: Contains 1 DHR-1 (CZH-1) domain. similarity: Contains 1 DHR-2 (CZH-2) domain. similarity: Contains 1 PH domain. subunit: Interacts with CDC42.

• UniProt :

  Q5JSL3

• Swiss Prot :

  Q5JSL3

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from part region of human protein

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  228kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  228kD

• Fragment :

  IgG

• Subcellular Location :

  Intracellular, cytosol

• Gene ID (Human) :

  139818