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VMAT1 rabbit pAb

CAT: 0855-ES9536-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9536-01Size:50 µL
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Background
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]) . See also SLC18A2 (MIM 193001) .[supplied by OMIM, Mar 2008]
Description
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al. 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001). [supplied by OMIM, Mar 2008],
UniProt
P54219
Swiss Prot
P54219
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
57kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
57kD
Fragment
IgG
Subcellular Location
[Isoform 1]: Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein .; [Isoform 2]: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Gene ID (Human)
6570

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