CLCN5 rabbit pAb

• Background:

  Chloride voltage-gated channel 5 (CLCN5) Homo sapiens This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]

• Description:

  Chloride voltage-gated channel 5 (CLCN5) Homo sapiens This gene encodes a member of the ClC family of Chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013],

• Gene ID:

  1184

• UniProt:

  P51795

• Cellular Locus:

  Golgi apparatus membrane ; Multi-pass membrane protein. Endosome membrane ; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from part region of human protein

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  82kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  82 kD

• Subcellular Location:

  Golgi apparatus membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .

• Gene ID (Human):

  1184

• SwissProt (Human):

  P51795