CAPS2 rabbit pAb

CAT: 0855-ES9476-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES9476-01Size:50 µL
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Background
Calcium dependent secretion activator 2 (CADPS2) Homo sapiens This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
Description
Calcium dependent secretion activator 2 (CADPS2) Homo sapiens This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009],
UniProt
Q86UW7
Swiss Prot
Q86UW7
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
142kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
142kD
Fragment
IgG
Subcellular Location
Cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, synapse. Membrane-associated to vesicles. Strongly enriched in synaptic fractions. Probably localizes to different vesicles compared to CADPS. Enriched on vesicular structures in the parallel fiber terminal of granule cells that are distinct from synaptic vesicles.
Gene ID (Human)
93664

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