AFF4 rabbit pAb

• Background :

  The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins (5;11) (q31; q31q23) . [provided by RefSeq, Oct 2011]

• Description :

  The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins (5;11) (q31;q31q23). [provided by RefSeq, Oct 2011],

• UniProt :

  Q9UHB7

• Swiss Prot :

  Q9UHB7

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from human protein . at AA range: 30-110

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  127kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  127kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus . Associates to transcriptionally active chromatin but not at snRNA genes. .

• Gene ID (Human) :

  27125