AFF4 rabbit pAb

• Background:

  The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins (5;11) (q31; q31q23) . [provided by RefSeq, Oct 2011]

• Description:

  The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins (5;11) (q31;q31q23). [provided by RefSeq, Oct 2011],

• UniProt:

  Q9UHB7

• Swiss Prot:

  Q9UHB7

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human protein . at AA range: 30-110

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  127kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  127kD

• Fragment:

  IgG

• Subcellular Location:

  Nucleus . Associates to transcriptionally active chromatin but not at snRNA genes. .

• Gene ID (Human):

  27125