COX2 rabbit pAb

COX2 rabbit pAb

• Description: Cofactor: Copper A. Disease: Defects in MT-CO2 are a cause of Cytochrome c oxidase deficiency (COX deficiency) [MIM: 220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood. Disease: Defects in MT-CO2 are associated with tumor formation. function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from Cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. similarity: Belongs to the Cytochrome c oxidase subunit 2 family.
• Gene ID: 4513
• UniProt: P00403
• Cellular Locus: Mitochondrion inner membrane ; Multi-pass membrane protein.
• Host: Rabbit
• Species Reactivity: Human, Rat, Mouse,
• Immunogen: Synthesized peptide derived from human protein . at AA range: 40-120
• Clonality: Polyclonal
• Validated Applications: WB, ELISA
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: WB 1:500-2000 ELISA 1:5000-20000
• Molecular Weight: 24kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.