COX2 rabbit pAb

• Background:

  Cofactor:Copper A., disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood., disease:Defects in MT-CO2 are associated with tumor formation., function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1., similarity:Belongs to the cytochrome c oxidase subunit 2 family.

• Description:

  Cofactor: Copper A. Disease: Defects in MT-CO2 are a cause of Cytochrome c oxidase deficiency (COX deficiency) [MIM: 220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood. Disease: Defects in MT-CO2 are associated with tumor formation. function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from Cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. similarity: Belongs to the Cytochrome c oxidase subunit 2 family.

• UniProt:

  P00403

• Swiss Prot:

  P00403

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from human protein . at AA range: 40-120

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  24kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  24kD

• Fragment:

  IgG

• Subcellular Location:

  Mitochondrion inner membrane ; Multi-pass membrane protein .

• Gene ID (Human):

  4513