COX2 rabbit pAb

CAT: 0855-ES9124-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES9124-01Size:50 µL
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Cofactor:Copper A., disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood., disease:Defects in MT-CO2 are associated with tumor formation., function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1., similarity:Belongs to the cytochrome c oxidase subunit 2 family.
Description
Cofactor: Copper A. Disease: Defects in MT-CO2 are a cause of Cytochrome c oxidase deficiency (COX deficiency) [MIM: 220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood. Disease: Defects in MT-CO2 are associated with tumor formation. function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from Cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. similarity: Belongs to the Cytochrome c oxidase subunit 2 family.
UniProt
P00403
Swiss Prot
P00403
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
24kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
24kD
Fragment
IgG
Subcellular Location
Mitochondrion inner membrane ; Multi-pass membrane protein .
Gene ID (Human)
4513

Popular Products