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U2AF1 rabbit pAb

CAT: 0855-ES9047-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9047-01Size:50 µL
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Background
This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Description
This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
UniProt
Q01081
Swiss Prot
Q01081
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 60-140
Target
U2AF1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
26kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
26kD
Fragment
IgG
Subcellular Location
Nucleus . Nucleus speckle .
Gene ID (Human)
7307

UniProtKB · Q01081

Splicing factor U2AF 35 kDa subunit

U2AF1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q01081
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
U2AF1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q701P4, Q71RF1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Disease

Disease variant

Ligand

Metal-bindingZinc

Biological process

mRNA processingmRNA splicing

Cellular component

NucleusSpliceosome

Domain

RepeatZinc-finger

Molecular function

RNA-binding

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