BCL3 rabbit pAb

• Background :

  This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008]

• Description :

  This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008],

• UniProt :

  P20749

• Swiss Prot :

  P20749

• Reactivity :

  Human; Rat; Mouse; ; Goat

• Immunogen :

  Synthesized peptide derived from human protein . at AA range: 340-420

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF; WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  49kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  49kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus. Cytoplasm . Cytoplasm, perinuclear region . Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation. .

• Gene ID (Human) :

  602