ACO2 rabbit pAb

• Background:

  The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008]

• Description:

  The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008],

• UniProt:

  Q99798

• Swiss Prot:

  Q99798

• Reactivity:

  Human; Mouse; Rat; Canine

• Immunogen:

  Synthesized peptide derived from human ACO2. at AA range: 421-470

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/5000.Not yet tested in other applications.

• Molecular Weight:

  90kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  90kD

• Fragment:

  IgG

• Subcellular Location:

  Mitochondrion .

• Other Product Names:

  Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)

• Gene ID (Human):

  50