Thioredoxin rabbit pAb

CAT: 0855-ES8834-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES8834-01Size:50 µL
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Background
The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Description
The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Product Name Alternative
Thioredoxin (Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP)
UniProt
P10599
Swiss Prot
P10599
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human Thioredoxin. at AA range: 52-101
Target
Thioredoxin
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
Buffer
-20°C/1 year
Molecular Weight
12kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
12kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Secreted . Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA) (PubMed:9108029) . Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054) . Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054) . Secreted by a leaderless secretory pathway (PubMed:1332947) . .
Other Product Names
Thioredoxin (Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP)
Gene ID (Human)
7295

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