PACAP rabbit pAb

• Background:

  Function:May be involved in regulation of apoptosis., induction:Down-regulated in primary B-cells early after ligand-stimulated activation., subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus., subunit:Isoform 2 interacts with CASP2 and CASP9., tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.

• Description:

  Function: May be involved in regulation of apoptosis. induction: Down-regulated in primary B-cells early after ligand-stimulated activation. subcellular location: In (PubMed: 11350957) diffuse granular localization in the cytoplasm surrounding the nucleus. subunit: Isoform 2 interacts with CASP2 and CASP9. tissue specificity: Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.

• UniProt:

  Q8WU39

• Swiss Prot:

  Q8WU39

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthetic peptide from human protein at AA range: 1-50

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  IHC-p 1:50-200, ELISA 1:10000-20000

• Storage Conditions:

  -20°C/1 year

• Fragment:

  IgG

• Subcellular Location:

  [Isoform 1]: Endoplasmic reticulum lumen . Secreted .; [Isoform 2]: Cytoplasm . Diffuse granular localization in the cytoplasm surrounding the nucleus (PubMed:11350957) .

• Other Product Names:

  Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein; pERp1; Proapoptotic caspase adapter protein)

• Gene ID (Human):

  51237