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PACAP rabbit pAb

CAT: 0855-ES8756-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8756-01Size:50 µL
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Background
Function:May be involved in regulation of apoptosis., induction:Down-regulated in primary B-cells early after ligand-stimulated activation., subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus., subunit:Isoform 2 interacts with CASP2 and CASP9., tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.
Description
Function: May be involved in regulation of apoptosis. induction: Down-regulated in primary B-cells early after ligand-stimulated activation. subcellular location: In (PubMed: 11350957) diffuse granular localization in the cytoplasm surrounding the nucleus. subunit: Isoform 2 interacts with CASP2 and CASP9. tissue specificity: Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.
UniProt
Q8WU39
Swiss Prot
Q8WU39
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic peptide from human protein at AA range: 1-50
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
[Isoform 1]: Endoplasmic reticulum lumen . Secreted .; [Isoform 2]: Cytoplasm . Diffuse granular localization in the cytoplasm surrounding the nucleus (PubMed:11350957) .
Other Product Names
Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein; pERp1; Proapoptotic caspase adapter protein)
Gene ID (Human)
51237

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