DC-LAMP rabbit pAb
CAT:
855-ES8699-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DC-LAMP rabbit pAb
- Description: Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al. 1998 [PubMed 9768752]). [supplied by OMIM, Dec 2010],
- Synonyms: Lysosome-associated membrane glycoprotein 3 (LAMP-3;Lysosomal-associated membrane protein 3;DC-lysosome-associated membrane glycoprotein;DC LAMP;Protein TSC403;CD antigen CD208)
- Gene ID: 27074
- UniProt: Q9UQV4
- Cellular Locus: Cell surface. Lysosome membrane ; Single-pass type I membrane protein. Cytoplasmic vesicle membrane ; Single-pass type I membrane protein. Early endosome membrane ; Single-pass type I membrane protein. During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3 (PubMed:9768752). Detected on lysosomes in mature dendritic cells (PubMed:9768752)..
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse,
- Immunogen: Synthetic peptide from human protein at AA range: 261-310
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
- Molecular Weight: 44kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.